Insulin infusions are administered through subcutaneous tissue injections to counteract a buildup of glucose in the blood throughout day.
Repeated insertions and chronic insulin exposure compromises the small volumes of subcutaneous tissue under the skin into which patients inject their syringes, pens and infusion set cannulas.
The changes in subcutaneous tissue can lead to infusion site abnormalities, which could reduce the efficacy of the insulin being used and lead to hazardous consequences to those living with this diabetes.
*Current medication delivery devices are not able to effectively detect when abnormalities are occurring during insulin delivery.*
>60% of insulin pump users experience infusion set failures
$426M per year is wasted by injecting into unviable sites
$4.2B value of global insulin pump technology industry
120M+ infusion sets used across the world every year
A successful infusion has insulin being deposited into the subcutaneous layer where it gets absorbed into the bloodstream via the blood vessels in the tissue.
An infusion site leak can happen if the cannula has been improperly inserted or if the injection site has been damaged during normal use. Currently, there is no way of detecting a leak at the infusion site.
An infusion site blockage can happen if the cannula is injected into damaged skin tissue or kinks during a faulty insertion. Blockages may produce a build up of insulin that could release into the body resulting in an overdose of insulin.
An infusion site dislodgement is when the cannula comes loose/gets removed from the site of injection. Dislodgements cause the adhesive pad to unstick from the injection site and severely alter the integrity of the injected cannula.
Damaged tissue can compromise proper insulin infusion rendering them ineffective at absorbing insulin compared to a healthy site. Skin conditions can arise from damaged sites; they build up over time in insulin pump users and can be irreversible.
Our new sensor-based system for insulin pumps has three main functions: monitor, diagnose and predict. It monitors the insulin delivery by looking for abnormalities, diagnoses the cause of the issue, and predicts when it will occur at different infusion sites.
We want our system to know the exact time at which their infusion set needs to be changed. Our biggest differentiator is our system’s ability to monitor infusion site performance and tissue health. DiaTech aims to revolutionize insulin delivery monitoring and minimize loss of insulin from failed sites.